Monday, December 30, 2019

Ethical Hacking Final Challenges Free Essay Example, 1000 words

Both ports 20 and 21 are known as random ports. While 21 is known as the TCP and is well designed for FTP control, the port 20 is the active FTP type and is designed for the actual transfer of data. Ports 23, 25, 53 and 110 are ports outside the range and they would be used to transfer actual data without the specified range. 23 is the Telnet, 25 acts for the simple mail transfer, 53 is the domain name saver and 110 acts as the Post Office Protocol version 3 (Simpson, 2006). In analyzing the services currently running for the Alexander Rocco Corporation, the ports being used must be keenly looked at to enhance the recovery of the ways to be used to curb the vulnerabilities. Challenge 3 Ethics and morality most so in the computer environment more or less revolves around the same thing that is ethics being a moral philosophy where one makes a moral choice and sticks to it. In our case it refers to the moral guidelines that an individual sticks to when using computers and computers networks including the encryption algorithms. We will write a custom essay sample on Ethical Hacking Final Challenges or any topic specifically for you Only $17.96 $11.86/pageorder now It is unethical and therefore against the law to do the following when it comes to computers and computer networks. An individual should not indulge into using office computers to do personal work, one should never read information not theirs either form email or from a friends networking sites without the friends permissions. Plagiarism which is the use of another persons work from the net without recognizing them is a crime that none should be found committing. As has been recorded in the past from computer crackers and hackers, one should never be found sending any form of computer virus via email to any computer or computer network. One should never hack into the systems of other individuals or organization, at the same time pirated software should never be sold in the market whether at night or at day time (Simpson, 2006). It should be noted that the learning and the reimplementation from open source software is a violation of the licence hence against the law whether morally or legally and it attracts a penalty of more than $25,000 or both. When and algorithm licence expires it ought to be replaced with another given that learning from search open source projects will be regarded as plagiarism. The illegality is also reinforced from the fact that such information is not enforced by the copyright laws. Derived from this, people who posses the ability to break into a hashing algorithm and post their findings into the internet must be arrested and arraigned in court given the extent of the illegality of their acts.

Sunday, December 22, 2019

Research Study On Online Dating - 1300 Words

The most rapidly developing demographic for those seeking dates online might just surprise you. In fact, according to research conducted by gerontology experts, not only do people over 50 now engage regularly in online dating website, but the demographic of people older than 60 are the most rapidly flourishing age group seeking dates online! With this idea in mind, consider that some features most commonly added to websites geared towards dating for those, who are 50 plus are quite similar across the board, but in addition to being over 50, consider the website that best suits you personal needs that offers screening, safety, and features that you enjoy the most and find makes the site easiest to use for you. Preferences vary within your age group among the over 50 dating sites highlighted below. Keep in mind that price is a factor, too. Some sites offer free trial so you can take a test run and see how the initial period works out for you, but some sites are either entirely free or offer a free membership type that offers less features than a paid one. This list should help you sort through your preferences and locate an over 50 dating website that s the right choice for you! Howaboutwe.com (AARP Dating) A recent partnership between AARP, which is an organization that is specifically geared towards improving the life of people over 50, and Howaboutwe.com has recently launched a dating service together that targets people over 50. This amazinglyShow MoreRelatedThe Changing Temperaments Of Cultural Practices Essay1496 Words   |  6 Pagescommonplace of the internet has allowed online dating to become a progressively popular and socially accepted way to meet significant others. According to the PEW Research Center (2016), 15% of adults in the United States have used online dating sites, while 41% of adults say they know someone who uses online dating. Unfortunately, the prevalence of online dating has opened up a way for malevolent behavior to flourish over the internet. With that being said, online scammers have configured an intimateRead MoreOnline Dating And Its Effects On The Internet Dating World1197 Words   |  5 Pagesup to the emergence of online, social dating. These onlin e dating site have change the way relationships interact, gossip, flirt and communicate. However, numerous people do not understand the deception and manipulation aspect that comes with online dating. Forming a passionate relationship over the internet under false pretense can be emotionally destructive. Several studies have been performed in an attempt to explain and understand the non-traditional world of online dating. The sources exploreRead MoreHow Online Dating Has Altered The Process Of Relationships1697 Words   |  7 Pagesschool online, buy all of your groceries from your home, and make video conference calls around the world. Naturally, in order to meet these desires, the world of online dating has flourished. Millions of people are signing up for a variety of websites that guarantee happiness for all different types of people. For those who can’t seem to find the time to go out and meet other singles in their community, online dating is seen as a quick and conven ient way to discover relationships. Online dating hasRead MoreWhat Does The Newest Research Tell Us About Online Dating?996 Words   |  4 PagesWhat does the newest research tell us about online dating? Why is the industry so powerful? How does it work? What are the real risks and dangers of online dating? The innovation of online dating did not even enter the vocabulary of romance until the end of second millennium, following the fast advances of the technology and the internet. In the last decade, searching for romantic partners via online dating sites has become a visible and common strategy for those looking for companionship. As ofRead MoreAn Inside Look at 0nline Dating Essay1547 Words   |  7 PagesOnline Dating Online website allows individuals to contact and communicate with others through the Internet each. It follows the sociological principle of social networking. The quest of love has inspired people to invest in much thoughts and efforts in the process of building a romantic relationship. Thus, online dating becomes a popular tool for building a relationship or starting a relationship nowadays. In addition, in order to accomplish the goal of finding the perfect partner there are manyRead MoreThe Boom Of Online Dating955 Words   |  4 PagesThe Boom of Online Dating According to Smith and Anderson in the Pew Research Center website, Americans now accept online dating as a good way to meet people. These findings differ from those of their first study in 2005, when most Americans believed that meeting people on the internet was inadequate. And even though people may think online dating is an inferior way to experience love, they probably know someone who met online or someone searching for a love on the internet. A analysis made byRead MoreOnline Dating Services Are Wonderful Way to Meet Compatible Potential Partners866 Words   |  4 Pages * Online Dating Services Are Wonderful Way To Meet Compatible Potential Partners * Adam Ali, Bob Crawford * CISC 497 - 002 * The rapid advancement of the Internet and the thousands of online dating websites is changing the way we seek out potential mates. Instead of heading down to the local bar or nightclub in hopes of finding that special someone, more people are at home, meticulously constructing descriptive verses of themselves for their online dating profile. Some of the biggestRead MoreHow The Internet Has Become A Major Vehicle For Social Interactions1187 Words   |  5 Pagestext messages, emails, and online chatting. This social stigma is up for much debate on how it relates to the progression in romantic relationships. This literature review focuses on how the Internet is utilized as a supportive method of courting used by individuals to meet online in hopes of forming a romantic relationship. Counterarguments suggest that online communication expands social interaction because it connects you to a plethora of people at a fast rate. The research of Cooper and SportolariRead MoreOnline Dating : The Negative Side Of Finding Significant Others Over The Internet1596 Words   |  7 Pagesay, 2017 Online Dating: The Negative Side of Finding Significant Others Over the Internet Before the birth of technology and social media, people approached their significant others face-to face. They encountered their future wives or husbands at schools, malls, markets, libraries or at any physical places. Everyone came to know others by recognizing their real faces, hearing their real voice, and understanding their real personalities. However, as the trend of using technological devicesRead MoreDating Online Essay1259 Words   |  6 PagesWhen navigating a dating app or website, searching and filtering tools allow daters to be more selective when finding a partner online than offline. Many enter the experience prepared with a desirable â€Å"shopping list’’ of characteristics and qualities a potential partner must have. source? There is little opportunity to reveal information gradually and check for reciprocity along the way. Instead, reciprocity is determined prior to any communication. Many potential partners who would be given the

Saturday, December 14, 2019

Rural Community Health Service Provisions Health And Social Care Essay Free Essays

string(272) " bit early as the twelvemonth 1969, those in political power have already recognized the deficiency of wellness attention staff willing plenty to shack in distant countries, for the interest of executing their pledged undertaking, to function the people in equal chances\." Chronic diseases can be a fatal, yet, returns on gradual procedures toward morbidity and mortality that include cardiovascular diseases, both types of diabetic conditions, and hapless respiratory position. These conditions are mostly related to the life style that persons lead, with their consumptive wonts of dietetic nutrients, baccy and intoxicant ingestion, as accompanied by physical activity modus operandis ( Halpin, Varela A ; Martin-Moreno, n.d. We will write a custom essay sample on Rural Community Health Service Provisions Health And Social Care Essay or any similar topic only for you Order Now ) . In a survey on the incidence of cardiovascular conditions in some developed states of North America and Europe, it had revealed that hypertensive episodes in older age groups had been more controlled in the former bunch, with Canada included, compared to the higher survey results in the latter, 8 % and 23 % severally ( Wolf-Maiser, et al. , 2003 ) . The better direction strategy in the North American opposite numbers could hold demonstrated better wellness attention systems, yet, reverse could still be observed in such locations. At this point, the chronicity of diseased instances prevalent in older age groups seemed to further expose them to vulnerable state of affairss, topped with the devolving physiological maps associated with progressing phase of chronological adulthood. As such, higher incidence of cardiovascular diseases with older age brackets appeared to present a serious community issue that requires close examination and inclusion of wellness reforms to holistically back up their present position. In peculiar, the distribution of wellness attention services in Canada ‘s rural communities had been identified as one of the important countries that seemed to be neglected in the bureaucratic procedure in wellness reforms. Unlike any definition on rural construction, Slack, Bourne A ; Gertler ( 2003 ) admitted that the state do non hold clear differentiation of what rural community is, depicting non-urban zones as rural in construction. Compared to the wellness services provided in the urban countries of Canada, the farness of several of its rural units had been fraught with several defects in wellness services, with inclusions in primary wellness unavailability, lower wellness forces figures, and hapless attention installations, as geographic distance and lifestyle position are said to be deteriorating in these countries ( Ryan-Nicholls, 2003 ) . As such, the job of cardiovascular diseases with older age groups had been compounded with the want of quality wellness services that should hold been more both timely and well-supported by involved wellness sectors As portion of the job associated with wellness attention in rural communities, wellness forces and societal public assistance officers have the primary duty to look at the general and wellness public assistance of the citizens in the community, particularly the defenseless groups of both immature and old age bunchs, yet treatments above revealed the lower keeping rates of wellness staff in rural units. The job with this is non the low work force in wellness workers, but instead, there appeared to be an unequal distribution of labour force between rural and urban locations ( Ryan-Nicholls, 2003 ) . Acknowledging the root of wellness attention forces deficits, such reverse seemed to add to the lifting job of ageing population in Canadian communities. At big, Arah, Klazinga, Delnoij, Asbroek, and Custers ( 2003, p. 384 ) emphasized that despite the wellness attention duties centered on wellness forces, reform in primary attention will still come from parts in other related sectors, such as the networking commissions in â€Å" national, regional and local degrees. † With the prevailing tendency of wellness publicity in Canada ‘s wellness system, the function of the bureaucratic authorities in support service plans for the ageing population had been established ; yet, subsequent studies demonstrated oversights in following through the undertaking plans towards the execution and existent direction stage. Hence, such projected wellness publicity efforts appeared fall more in ineffectual efforts-federal engagement had been well limited in local community enterprises ( Boyce, 2002 ) . The wellness attention issue in rural communities, affecting ageing populations with cardiovascular conditions, so, would necessitate the conjunct attempts of the local wellness forces, every bit good as the national wellness commissions responsible for resource support and allotment of just and quality services to remote rural countries in Canada. Literature Review Canada is a state with well-managed resources, and as its population grows, so will the demands of the people become higher. As emphasized by Clark and Leipert ( 2007 ) , the incidence of widening figures in the older age groups, runing from 65 old ages old above, had caused ruffling effects in its aftermath. On one manus, their worsening wellness that had been combined with cardiovascular conditions indicates that they need more clinical aid more. On the other, their age prevents them from happening employment as their physiological and mental wellness are said to by and large worsen with the rise of figures in their age. Such observations had been relevantly reflected in several surveies conducted in European states. Peoples nearing center to old age exhibited higher medical outgos compared to those in really old age ( 85 old ages old and above ) ( Rechel, Doyle, Grundy and Mckee, 2009 ) . At which point, ingestion of medical intervention may accountably lift when old persons belie ve that they have better opportunity of widening their lives beyond 65 old ages old, bring forthing more government-assisted wellness services in the long tally. Their medical attention non merely consists of availing the services of clinical installations and wellness suppliers, but besides the medicine supplies and place attention care particular in their status, like in persons with cardiovascular conditions. More common than non, there is hapless attachment to order medicines as the costs can non afforded by persons with lower income ( Mojtabai A ; Olfson, 2003 ) . In the instance of old population who are retired, there is no generated income at all, merely the retirement pensions for some. There are personal jobs that these groups had to face, and these are reflected on the quality of wellness they sustain. Historically, rural communities had long since experienced the job of reverses associated with delayed wellness commissariats from the cardinal authorities well funding the national wellness plans. In every bit early as the twelvemonth 1969, those in political power have already recognized the deficiency of wellness attention staff willing plenty to shack in distant countries, for the interest of executing their pledged undertaking, to function the people in equal chances. You read "Rural Community Health Service Provisions Health And Social Care Essay" in category "Essay examples" Yet, it seemed that by the passing of the decennaries, such job had non lessened with clip, this, alternatively, became a grim instance of reduced attention practicians in such locations, where at that place used to be a solo wellness supplier in every communities, now, they have become more scarce in several 1s ( Pong A ; Russell, 2003 ) . In line with this, the laterality in big medical establishments h ad shifted towards community wellness Centres and smaller attention clinics in the late sixties ( Groene A ; Garcia-Barbero, 2001 ) . At this point, it must be recognized that no affair how updated the installations are and how willing the community citizens undertaking in collaborating for better wellness allowances, they all will be in vain when there are no wellness attention staff to ease such resources in the field. In such scenario, it appeared that oversights in support from higher authorities sectors had led to decomposition of wellness attention structures in the said countries. In the traditional design followed by Canada ‘s wellness sector section during the late fifties, no specific policies had been constructed in every bit administering wellness forces on the different countries in the state. Such deficiency of systematic attack had been dramatically revised in 1966, where practising medical forces have more autonomy in puting private pattern for definite fees, restricting wellness services that are low-cost in the state. Acknowledging a figure of disagreements with such clinical freedom, federal authorities placed more stiff parametric quantities to protect consumer rights, punctually supplying for services that are out of privately-insured medical strategies, such as â€Å" place attention, nursing places, outpatient pharmaceuticals † ( Tuohy, 2002 ) . As observed in such authorities reforms in wellness, precedences had been more on administering more wellness services to more people, ignoring the equal chances for communities to obtain wellness forces to help in their wellness issues. Aid in rural locations, particularly the fiscal 1s, is transferred from the Provincial divisions through established transportation undertakings. The ideal system postulate that the divider of authorities ‘s countries of duties into sub-divisions denote faster distribution and use of much demand commissariats and services, as the local scenes are given adequate entree to resources to ordain on issues that needs prompt actions ( Slack, Bourne A ; Gertler, 2003 ) . However, such scheme had presented several oversights, as it had non been plenty in turn toing the cut downing figure of wellness forces in rural communities, certifying that fiscal resources are non the lone country that require examination in turn toing wellness unfairness of old population-federal committedness for effectual primary attention reform should be strengthened. As authorities support is mostly required to advance communities that are well-sustained in back uping the demands of its local citizens, their function in the procedure of accomplishing such nonsubjective is critical. Retrospective surveies revealed the deficiency of consolidation between the divisions, federal and provincial systems, in authorities opinion and duties, as struggle on sum of financess transferred from federal to provincial offices had non been settle in the past decennaries. Revisions in the support transportation had taken topographic point during the 1995 budgetary cuts, allowing out several protests at the lower degree of the authorities offices in provincial subdivisions. Where some countries had still remained the precedence, such as wellness publicity schemes, and wellness installations, wellness policies back uping community wellness development through better supply of wellness attention staff remained written in commission studies, but ne’er to the full realized ( Tuohy, 2002 ) . With such complecting constructs on ageing population, cardiovascular conditions, and attendant habitation in distant rural countries, the class of progressing developmental age is more at hazard than any other age groups in the same state of affairs. The capacity of the topics in the survey to flexibly get by seemed to travel reciprocally with age. As such, this reappraisal of valid surveies had shown that small attending had been given to strip older persons. Relative with this, spreads on how to turn to the wellness conditions normally bing in persons, every bit good as reconstituting the primary attention construction, must be analyzed and given prompt and efficient attending, as their go oning tendencies may take to more unfairness that takes advantage of the clustered exposure of seniors shacking in distant rural communities. Discussion The primary issue of the paper centres on the combination of old age with chronic cardiovascular status and the deficiency of system support in rural communities, which increases the hazard for lower wellness attention commissariats and services. Noting such incidents, a figure of priority solutions can be recommended to ease the wellness unfairness imparted to this group. The events taking to this may be summarily explained through the sensed barriers to hapless primary wellness attention bringing: ( 1 ) work force scarceness, ( 2 ) sustainable Economic barriers, ( 3 ) geographical unavailability, ( 4 ) cognition shortages ( Hutchinson, Hawes A ; Williams, 2010 ) . As such, these may necessitate a comprehensive model of schemes which jointly reconcile each issue towards more effectual wellness attention construction. The efficient attacks in guaranting that older population have the critical wellness plans they need are to prosecute in the run towards â€Å" wellness publicity and disease bar † ( Burns, 2006 ) . The precedences of such constructs had been clearly delineated in the Ottawa Charter, particularly in the former context. This international end chiefly calls for the shared committedness of meeting stakeholders and involved parties in guaranting an efficient model that pursues wellness, above all. Particularly, the said committee had listed the entities involved in such an embracing wellness committedness, including â€Å" persons, community groups, wellness professionalsaˆÂ ¦institutions and authorities, † appealing that they abide with each of their duties in prolonging excellent for all, particularly the vulnerable ripening groups ( Lopez-Acuna, Pittman, Gomez, de Souza, A ; Fernandez, 2000 ) . Medical schemes are non the primary focal point of the said end ; alter natively, it goes manner beyond the healing side to advance a wellness organisation that holistically meets the demands of possible clients in communities-physically, cognitively, psychologically, and spiritually. With the changing demands of ageing population with chronic conditions, a multi-dimensional declaration of perceived jobs may be required in this scenario. In a conceptual model observed in Figure 1 ( delight see Appendix A ) , it well review the general barriers to wellness development of rural community as a whole and ageing populations with chronic disease in peculiar. Schemes to hapless wellness conditions of ageing population in rural communities must non merely turn to their individualised conditions, as considerations on other societal and environmental factors environing these groups must besides be given sufficient attending. More significantly, the roots of the job must be addressed judiciously in order to continue in executing efficient wellness attention publicity and disease intercessions for the targeted group, the aged citizens. As identified earlier, there are five extenuating barriers to the hapless conditions of rural wellness units, and the people shacking in such countries. Earlier subdivisions in the paper had comprehensively reviewed the struggles between two divided subdivisions of the authorities, the federal and provincial authorities offices. As such, their budgetary differences seemed to halter the flow of resource support towards relevant wellness plans, likely decelerating the operations of receiver sectors that require attending, such as wellness attention constructions and issues. Through amalgamate and collaborative attempts by both authorities divisions, the flow of resources that will fund executable plans can be initiated and procedurally executed. In Action Plan instigated by the Canadian authorities in 1998, wellness promoting attacks, wellness communicating links, installations and wellness constructions had been given adequate precedence, while wellness work force and pharmacological supports had been left behind ( Tuohy, 2002 ) . In the proposed plan, all subdivisions needed in communities, particularly the rural countries, will be decently meted. . Workforce scarceness. Nursing forces deficits, particularly physicians and nurses, seemed to prefer big infirmary establishments in urban countries, instead than remain and function in tranquil and friendly vicinities in rural communities. As such, a figure of attacks can be recommended in pulling the involvement of wellness forces into rural locations. For one, the influence of pecuniary compensations can be one country to fulfill in professional workers. For another, satisfaction besides comes with the efficaciousness of wellness forces in their work environments. With updated and well-supplied wellness equipments and supplies, wellness professional can carry through their pledged responsibilities without negative feelings as they can execute significant undertakings for the community and its citizens, while maintaining their households near in supportive plans that finance several constituents of wellness staffs ‘ household members with them ( Pong A ; Russel, 2003 ) . With more wellness forces flocking rural communities, better wellness attention proviso can be rendered, and wellness instruction can be offered to seniors enduring from chronic conditions. Sustainable economic barriers. Government funding can non last in prolonging community development and its growing. At the initial stage, provincial sector of the authorities can supply for resources in get downing up community undertakings that may heighten the flow of economic gross towards rural communities. The chief economic issue in rural communities is that these units offer businesss that are non diversified in character, where professionals tend to look for occupations elsewhere as they lack the necessary comfortss to hike micro-business that could hold provided occupations for more local people. With this being the instance, authorising the citizens to move can be disputing. Like most enterprises, injection of fiscal capital for purchase of necessary resources is required to incite plans that address the economic demands of communities. For case, â€Å" Ontario Small Town and Rural Development Initiative ( OSTAR ) † had been established to assist the indicated sector in stabilising local economic systems and substructures ( Enid, Bourne A ; Gertler, 2003 ) . Local organisers have the duty to take the remainder of the citizens towards preparation activities and concern ventures that may likely pull in occupations from suburban countries, and can even undertakings a sustainable position that depends less on provincial authorities in shouldering community betterments, such as local building costs and other plans related to better selling and consumer engagement in sceptered communities. Geographic unavailability. As Canada is non far behind its neighbouring world power states in economic advancement and enlargement, the issue of geographic distance could hold been easy resolved through modern agencies of communicating. The debut of medical specialty in the context of computerized engineerings had been introduced a few old ages back. Through the external supports attached with such technological inventions, picture cyclosis and Internet-based synergistic conversations can be possible. Termed as telemedicine, such scheme covers the distance between wellness suppliers and receivers during the proviso of attention and services ( Hutchinson, Hawes A ; Williams, 2010 ) . Alternatively of aged patients with chronic conditions going far merely to run into their physicians for scheduled check-ups, this population can use their computing machine units in making so, without the excess disbursal and attempts. Health forces at certain distances can be accessed through practical medium, from their ain places. Knowledge Deficits. With such reverse in several rural communities, aged people can non be updated with the true nature of their conditions. The deficiency of cognition on how to continue with ageing position can be compounded with low resources and uncoordinated webs in local rural zones to advance wellness consciousness. Through wellness publicity attacks, factual information can be distributed in timely and effectual ways. There are a assortment of ways in executing such ends, such as community consciousness, information thrusts, persuasion in societal policy alteration, go oning preparation and instruction, and active runs which demonstrate better wellness position ( Laverack A ; Labonte, 2000 ) . Performing most of them, it is rather safe to state that lifestyle alteration, avoiding destructive baccy and intoxicant wonts while keeping better diet and exercising degrees, particularly in cardiovascular diseases in aged can be controlled. Furthermore, medicine regimen can be bette r complied, as this plays a portion in commanding several sorts of bosom diseases, such as high blood pressure ( Halpin, Varela A ; Martin-Moreno, n.d. ) . These schemes must be systematically drilled in community scenes, concentrating on aged groups who are more vulnerable than the remainder. When there is betterment in wellness behaviours and informational follow-through in ageing population, they have better opportunity at forestalling farther patterned advance of acquired wellness conditions ; merely so can the enforced plans on wellness publicity and disease bar be viewed as partly successful in accomplishing community ends of better wellness through the coaction of different sectors in such schemes. Decision All in all, the job in older populations had converged, with inclusions of high prevalence of developing chronic cardiovascular conditions, and societal unfairnesss brought approximately by shacking in rural countries. Sing their distance from big infirmary establishments, this group is at higher hazard of developing shortages in cognition sing their current wellness position, as rural communities seemed to be prone to work force deficits, but in wellness and economic sectors. Furthermore, it seemed that the great distance projected by rural communities seemed to drive big concern ventures, worsening jobs of community sustainability of its citizens. Sing the drawn-out differences between the federal and provincial authorities sing budgetary affairs, jobs in community subdivisions remained dead and unattended for most of the clip. As proposed in the paper, the authorities in Canada plays a critical function, particularly in its capacity to supply resources and sufficient support, in d eveloping the hapless wellness and communal conditions of several rural units. As such, fiscal and political support served stable anchors to induction of plans, from socioeconomic sustainability, set uping telemedicine connexions, and building effectual attacks in wellness publicity ; all these contribute in their alone facets in hiking the overall position of rural communities. For the ageing population, support in wellness and day-to-day life seemed hearty plenty for some, while others continue to be involved in community engagement, as several seek authorization and independency, peculiarly on pull offing wellness more quickly and efficaciously. How to cite Rural Community Health Service Provisions Health And Social Care Essay, Essay examples

Friday, December 6, 2019

Andy Warhol Short Biography Life and Death Essay Example For Students

Andy Warhol Short Biography: Life and Death Essay Andy Warhol was born in Pittsburgh, Pennsylvania in 1928 as Andrew Warhol. He graduated from the Carnegie Institute of Technology before moving to New York where his first big break, occurring in August 1949, took place. Glamour Magazine had asked him to illustrate an article called Success is a Job in New York. He had dropped the a in his last name When the credit mistakenly read Drawings by Andy Warhol. By 1355. Andy Warhol had almost all of New York copying his work. He was well known for creating ink images with slight color changes. Coca-Cola bottles and celebrity faces, such as Marilyn Monroe, were some of the popular items Andy Warhol did. Andy Whorls Campbell Soup Can is a classic and easily recognized piece of work. Andy Warhol also made many films about time, boredom and repetition like Empire and The Chelsea Girls, the classics that are underground now. With the privilege of working with the rock band were Velvet Underground in 965, Andy Warhol traveled around the country with not only The Velvets, but also with the 1965 superstar Edie Sedgwick and the lightship The Exploding Plastic Inevitable. On June 3rd, 1968, Valerie Solaris, founder and member of SCUM (Society for Cutting Up Men), walked into Whorls studio The Factory and shot him three time in the chest. He was rushed to the hospital and the doctors said he was dead. With the crazy idea of opening up his chest and massaging his heart just n case they could make him survive, Andy Warhol miraculously came back to life. Solaris turned herself in and was put into a mental institute, then was later given a three-year prison sentence. After recovering, Warhol continued to work. He had started interview magazine and published The Philosophy Of Andy Warhol: From A to B and Back Cain. Andy Warhol died on February 22nd, 1987 after a routine gall bladder surgery. With the result of his death, The Andy Warhol Museum opened in Pittsburgh in May.

Friday, November 29, 2019

Gregor Mendel Essays (101 words) - Biology, Genetics, Geneticists

Gregor Mendel Gregor Johann Mendel 1. Time in history: Mendel was born on July 22 1822 and died on January 6 1884 2. Country of Origin: He was born in Austria 3. Field Of Work: Mendel was one of the first scientist to study heredity and the science of genetics. 4. Notable Discoveries: Mendel was the first person to trace the characteristics of successive generations of a living thing. He was the first scientist to cross peas of different varieties. He also worked with mice. Known as the Father of Heredity Mendel's work became the foundation for modern genetics. 5. Famous Publications: N/A 6. Sources: http://www.gene.com/ae/AB/BC/Gregor_Mendel.html Compton's interactive Encyclopedia Science Essays

Monday, November 25, 2019

Free Essays on The New Frontier

Why Would Anyone Want To Travel To The New Frontier? Throughout history many people decided to abandon their civilized lives in the cities of the East Coast of America, and travel westward. These people were known as Frontiersman. They left everything they had in the cities, sometimes including their families and set out west. They set out in search of wealth and power that they could not acquire in the east. Many of the people that set out west were considered well built and tough. They were willing to take serious risks with no guarantee of any return. There were a few â€Å"frontiersman† that made it big the way they had hoped, unfortunately there were many more who did not. The life of a â€Å"frontiersman† was not for the faint of heart. There were fights between Indians and other â€Å"frontiersman†. Food was scarce because of the limit of civilization. All food had to be created or hunted in order for survival. There were many risks associated with living on your own hundreds of miles away from anyone else. The â€Å"frontier† lifestyle was not as glamorous as some people thought it to be. There were many dangers, and it was survival of the fittest at its best. Who in their right mind would want to do this? After the first frontiersman left and settled out to the west, many of them died just from the fact that they had to survive by themselves. For the ones that survived, living alone became boring. In the winters there was nothing to do but try and keep warm. During the summers they were constantly working. Many of them hunted beavers for their prized furs. They would skin the animal after catching them and when the wagon trails from the east came out with supplies, trade them in. This sounds pretty easy, however the people coming from the east with supplies such as rifles and tobacco knew they had a monopoly the goods they brought. They often raised the cost of the supplies to nearly 2,000 percent. (AFC ... Free Essays on The New Frontier Free Essays on The New Frontier Why Would Anyone Want To Travel To The New Frontier? Throughout history many people decided to abandon their civilized lives in the cities of the East Coast of America, and travel westward. These people were known as Frontiersman. They left everything they had in the cities, sometimes including their families and set out west. They set out in search of wealth and power that they could not acquire in the east. Many of the people that set out west were considered well built and tough. They were willing to take serious risks with no guarantee of any return. There were a few â€Å"frontiersman† that made it big the way they had hoped, unfortunately there were many more who did not. The life of a â€Å"frontiersman† was not for the faint of heart. There were fights between Indians and other â€Å"frontiersman†. Food was scarce because of the limit of civilization. All food had to be created or hunted in order for survival. There were many risks associated with living on your own hundreds of miles away from anyone else. The â€Å"frontier† lifestyle was not as glamorous as some people thought it to be. There were many dangers, and it was survival of the fittest at its best. Who in their right mind would want to do this? After the first frontiersman left and settled out to the west, many of them died just from the fact that they had to survive by themselves. For the ones that survived, living alone became boring. In the winters there was nothing to do but try and keep warm. During the summers they were constantly working. Many of them hunted beavers for their prized furs. They would skin the animal after catching them and when the wagon trails from the east came out with supplies, trade them in. This sounds pretty easy, however the people coming from the east with supplies such as rifles and tobacco knew they had a monopoly the goods they brought. They often raised the cost of the supplies to nearly 2,000 percent. (AFC ...

Thursday, November 21, 2019

Emergent bilingual Essay Example | Topics and Well Written Essays - 500 words

Emergent bilingual - Essay Example This group of individuals is born outside the country and speaks a different language other than English in their respective homes. They have insufficient mastery of English language that can help them meet the country’s standards and pass in any English test. (pg. 87 line 1-8) Garcia 2009 asserts that in most of today’s society, the most misunderstood issue in our education system is how the students who speak other languages that are not English related will be educated. Calling children this term of emergent bilinguals creates a positive characteristic as compared to the earlier term of English language learners that were used to refer to this group of individuals. This term does not suggest that these children have a limitation, but it suggests that they have the potential of developing bilingualism. These groups of children are noted to have an advantage over those children who only speaks English as their language, and they have difficulties in becoming bilinguals (pg. 322 lines 1-27). Bilinguals are known to can develop academic English if they are to be given the same opportunities on socioeducation as the other white children who are wealthy. A new curriculum and pedagogy that is equitable must adapt to the needs of emergent bilinguals. The inclusive curriculum that is challenging for emergent bilinguals must be adaptive ecologically as bilingual students, and biliteracy emerge. In early childhood, emergent bilingual at one point must have been given the opportunity to interact with caring adults and apart from speaking their home languages; they do understand their cultural practices. These adults also guided their bilingual development through providing the children with opportunities to practice how to speak and use English language. The language that the child is to use must occur in the home of the child’s language (GarciÃŒ a & Kleifgen,

Wednesday, November 20, 2019

Rhetoric anlysis Essay Example | Topics and Well Written Essays - 250 words - 2

Rhetoric anlysis - Essay Example rb indicates that Catton’s style does not emphasize on action images, but on descriptive images that aim to illustrate the paradox of being different, and yet being alike. Another example of atypical syntax is: â€Å"Daring and resourcefulness they had too† (paragraph 15). It is a typical because the predicate â€Å"Daring and resourcefulness† was put first before the subject â€Å"they.† The unique quality of writing emphasizes descriptions of the greatness of these two generals, and how they truly captured the diverse characters of the American identity. Catton focuses more on the backgrounds of the two generals and how they served as the metaphor of their people because they are more important than statistics and dates in representing the greatness of two people uniting for a great common cause. For instance, Catton says that â€Å"Lee†¦himself was the Confederacy† (paragraph 6) and Grant was â€Å"the Westerner† (paragraph 11). By making each general stand for the people they were fighting for, Catton successfully creates a patriotic tone that can unify Confederates and Union supporters because, if their generals, the epitome of who they are and what they stand for, can set aside their differences to attain common interests, then these two groups of people can also do the same. The single sentence in paragraph 3 provides the thesis of the essay. It argues that these two generals are truly different, but they must collide in order to pave a new direction for the country. The purpose of using a single sentence is to emphasize the thesis and to set the tone of writing and attitude of the speaker toward the values and ideals that Lee and Grant represent, individually and jointly. These coordinating conjunctions give special coherence to the paragraphs because they provide the signal posts for talking about differences or similarities between the two generals and the lives they represent. They also support the patriotic, conversational tone that Catton uses, so

Monday, November 18, 2019

Taking a Closer Look at Thailands Free Trade Agreement Essay

Taking a Closer Look at Thailands Free Trade Agreement - Essay Example The term "free trade" has become very politically loaded, and it is not uncommon for so-called "free trade agreements" to impose additional trade restrictions. Such restrictions on trade are often due to domestic political pressure by powerful corporate, environmental or labor interest groups. Free trade agreements are a key element of customs unions and free trade areas. The details and differences of these agreements are covered in their respective articles (Wikipedia Website). The spate of Thailand's bilateral FTAs had sprung from its intense need to supply more markets for its own exports after the failure of the WTO negotiations in the Doha Development Round. For others, this represents a shift in the Thai trade policy from multilateralism that Thailand advocated for two decades since it became a GATT member in 1982. Either way, new challenges abound for all parties due to this recent policy change leaning towards bilateralism and regionalism instead of multilateralism (Chirathivat & Mallikamas, 2004 p. 37). Before this, Thailand already built bilateral and regional trade ties with a number of trading partners in Asia and the world. In further improving the nature of its FTA policy, there will be implications for the country since many businesses there are not broadly multilateral. With regards to the impact of the FTAs, costs and benefits, and adjustment mechanisms are still being scrutinized. However, the government is strongly determined to realize these alternative liberalization paths and incorporate it as an integral part of Thailand's new trade strategy. To elaborate more on Thailand's pivotal decision of adapting new strategies in its FTA, Chirathivat & Mallikamas (2004, p. 40) mentioned that the financial crisis of 1997-98 could be the main reason. Thailand and generally the East Asian region felt the need to promote closer economic co-operation. Although regionalism is regarded as the second-best policy, many countries have started to explore this alternative. The effect of competitive liberalization contributed in a way to the rise in regionalism worldwide and also in East Asia and Thailand. The advantages should maintain "competitive liberalization" that would open up favorable markets and ease the regulations within the group, which would put an outsider country in a possible unfavorable situation. As a result, foreign companies with a presence in Thailand are currently shifting strategy to take advantage of its FTAs. For instance, Toyota Motor Corp. is shipping manual transmissions for pickup trucks from India to Thailand, and sending Corolla knockdown kits back the other way for assembly in India. Both items benefit from the lower tariffs of the FTA and greatly help increase Toyota's price competitiveness (Nagao, 2005). In addition, Japan is pressuring Thailand to eliminate import tariffs on cars with 3000cc engines and luxury cars over 3000cc before the seven-year period offering by Thailand. It seems Japan wants to increase import quotas of Japanese cars by 1-3 per cent of total production in Thailand. In fact, Japan has warned Thailand that its proposal on luxury cars is the most important

Saturday, November 16, 2019

Management of Childhood Psoriasis with Acitretin

Management of Childhood Psoriasis with Acitretin Abstract: Psoriasis is a chronic inflammatory disease of the skin which can occur at any age-group. Psoriasis in childhood is not uncommon and has genetic susceptibility but usually an environmental trigger such as infection is thought to initiate the disease process. Childhood psoriasis has profound effects on both physical and psychosocial health of the patient. Treatment of mild psoriasis can be done with topical therapies but those which do not respond to topical therapies can be treated with phototherapy and systemic therapies. The use of systemic therapies in childhood is mainly based on the published data, case series, expert opinion and the experience as there is lack of controlled trials in the age group. Based on the experience retinoid are probably the second line drugs for the treatment of childhood psoriasis which do not respond to topical therapies and phototherapy. Using acitretin in a low dose and with proper physical examinations and laboratory investigations will reduce the h azard of potential serious adverse events. This article gives the review of use of acitretin in the childhood psoriasis. INTRODUCTION: Psoriasis is the chronic inflammatory disease of the skin having the world wide prevalence of 1-3% and is clinically characterized by erythematous papules and plaques covered with silvery scales(1, 2). Psoriasis can occur at any age. Psoriasis in pediatric population is not uncommon and exerts a major impact on physical and psycho-social health of a child. In about one-third of the psoriatic population, the onset of disease is seen during the pediatric age(3). In a study of 419 patients from Northern India, the age of onset of psoriasis ranged from 4 days to 14 years(4). The presence of positive family history was found to be 23% and 34.3% in two different studies(5, 6). Pediatric psoriasis has the genetic susceptibility but the environmental factors often trigger the initiation of the disease process. The most common triggering factors include respiratory infection, sore throat, stress and trauma. There are different variants of psoriasis in children like plaque, guttate, napkin, er ythrodermic, pustular and nail psoriasis(2). Plaque psoriasis is the most common subtype and the pustular psoriasis is the least common subtype(7). Psoriasis in childhood and adolescence require proper management. Both the patient and the parents must be given the knowledge about the disease and its nature. Psoriasis in childhood affects the health-related quality of life. It is found that, the risk of mental illness like depression and anxiety is increased in children with psoriasis than those without psoriasis(8). Due to the presence of visible skin lesions the children with psoriasis suffer from the low self-esteem(9). Fortunately, childhood psoriasis is usually mild and can be treated with topical therapies. Systemic treatment is required only if the disease do-not respond to topical therapies, phototherapy and if the disease is significantly impairing the psychosocial aspect of the child health. Systemic therapies for psoriasis in children are not approved by FDA. Due to the lack of controlled trials use of systemic therapies are based on case reports, published data and expert opinion. On the basis of published data and experience retinoids appear to be the second-line drug of choice for children(10). ACITRETIN: Retinoids encompasses all the compounds either natural or synthetic, which possess the biological activity like vitamin A(11). Synthetic Retinoids are classified into three generations. Acitretin and etretinate are the second generation synthetic retinoids and are also known as aromatic retinoids(12, 13). Acitretin is the free and active metabolite of etretinate. Etretinate is strongly lipophilic and tends to accumulate more in the adipose tissue and thus has a longer elimination half-life, in contrast acitretin is less lipophilic and thus clears rapidly from the body and has the shorter elimination half-life(14).Intake with food increases the absorption of acitretin so, the bioavailability of acitretin is more when taken with food than on the empty stomach(15). Due to the longer elimination half-life of etretinate it has been largely replaced by acitretin. However, it is found that re-esterification of acitretin to etretinate can take place with the concomitant intake of alcohol. So , the female patient especially of childbearing age should be strictly instructed to not take alcohol during the period of treatment with and 2 months after the completion of treatment (16). USE IN PEDIATRIC PSORIASIS: Pediatric psoriasis is usually mild and topical therapies are the first choice of treatment. Systemic therapy is not the first choice in childhood psoriasis. It is used in the treatment of recalcitrant psoriasis which do not respond to topical therapy, phototherapy and if it is significantly impairing the psychosocial aspects of the child health. Due to the lack of controlled trials, the use of acitretin is based on the published data, case reports and the expert opinion. However, the significant risk benefit of the treatment should always be weighed with the risk of disease without treatment. Long term use of acitretin in children with inherited disorder of keratinization supports the safety of acitretin in children, but the monitoring is always required(17). Acitretin is used effectively in the treatment of generalized pustular psoriasis, erythrodermic psoriasis, palmoplantar psoriasis and severe recalcitrant plaque psoriasis but acitretin is not effective in psoriatic arthropathy( 12, 18). Acitretin is used as either monotherapy or in combination with topical agents and narrowband ultraviolet phototherapy. In a multicenter cohort study by Ergun et al. 61 patients among 289 patients were treated with acitretin at a dose of 0.3-0.5 mg/kg/day with the mean duration of treatment being 9.16+-9.06 months. 47.5% of the patient achieved at least PASI- 75 response. 70.7% of the patient well tolerated the treatment with no side effects. 25.9% experienced the mucocutaneous side-effects, 1.7% had hyperlipidemia and 1.7% had nausea(19). In a multicenter retrospective analysis by Lernia et al. including 18 children with plaque psoriasis ,8(44.4%) patient achieved a PASI-response 75 at 16 weeks. The starting dose of acitretin was 0.2-0.5mg/kg/day but the dose was increased to 0.6mg/kg/day in two patients after 8 weeks. Three out of eight patients achieving PASI-75 response stopped therapy for the interval of 2-6 months but had to restart the treatment after relapse and the treatment was effective even after re-introduction. 9 patient discontinued treatment due to lack of efficacy and 1 patient discontinued treatment due to arthralgia. All patients had the mucocutaneous side-effects like chelitis, dry lips, dry mouth and pruritus. The laboratory values of the patients were within the baseline during the treatment(20). Ergin et al. reported a case of infantile pustular psoriasis treated with acitretin with the initial dose of 0.5mg/kg/day which was later increased to 0.7mg/kg/day. The skin lesion was cleared in the end of 4 months and then the acitretin was tapered to 0.3mg/kg/day for three months and then discontinued. Oral prednisolone was used initially then it was tapered and discontinued. Slight increase in serum triglyceride was observed but it returned to normal after the dose was tapered. No other adverse events were observed(21). Salleras et al. reported a case of 4-year-old girl with congenital erythrodermic psoriasis treated with acitretin at a dose of 0.5mg/kg/day and the complete remission achieved in three months. The discontinuation of the drug led to relapse so the patient was maintained in 0.5-0.75mg/kg/day of acitretin during the aggravation of the disease. The patient was followed till 7 years of age and no other secondary effects were observed(22). A case of annular pustular psoriasis in a 14-month old girl reported by Haug et al. was treated with acitretin in the dose of 0.9mg/kg/day and the patient achieved complete remission after 4 months. The dose of acitretin was reduced and tapered at 0.1mg/kg/day and discontinued after 10 months with no relapse in the following three years. The patient experienced mild side effects like chelitis, reversible hypercholesterinemia and elevation of alkaline phosphatase(23). Acitretin is aa excellent option in a child with palmo-plantar psoriasis. A 14-year-old boy with palmo-plantar psoriasis treated with acitretin at a dose of 10mg/day had a good response with improvement within 6 weeks. At 3-month follow-up the patient had almost lesion free. The patient had experienced adverse events like mild chelitis and xerosis but the laboratory values remain unchanged. Later the patient was maintained on acitretin 10mg every other day together with the topical combination of 15% liquor carbonis detergens compounded in triamcinolone 0.1% ointment applied every night(24). Combination with other therapies: Acitretin has been used in combination with NB-UVB phototherapy, methotrexate and cyclosporine A(24, 25). The effect of acitretin together with NB-UVB is found to be synergistic. A case of 3.5-year-old boy with severe pustular psoriasis (von Zumbusch type) reported by kopp et al. was started on acitretin 1mg/kg/day with the short-term use of systemic methylprednisolone for controlling the acute stage. However, any attempt to reduce or discontinue the steroid led to exacerbation of the disease. Then the patient was given NB-UVB phototherapy three times per week. Later, after five exposures the corticosteroid was tapered and discontinued. The patient was then maintained on NB-UVB phototherapy two times weekly together with acitretin 0.3mg/kg/day. Disease was well controlled with this combination regimen. The laboratory values remained unchanged during the acitretin treatment(26). A 9-year-old boy with generalized pustular psoriasis was treated with acitretin 10mg/day and was maintained at 10mg three times week for a year. Later he developed skin pain and localized area of pustules which led to increase in the dose of acitretin 20mg/day during the flare but later tapered to 10mg/day for the next year. But the patient eventually required the addition of NB-UVB phototherapy to maintain the remission. The patient is well maintained by this combination(24). Adverse events of acitretin: Acitretin in known to exert a number of adverse events. Most of the adverse events are dose dependent and reverse back to normal after decreasing the dose or after discontinuation of therapy. However, it is usual to have the minor side-effects on the long term treatment with acitretin. The most common adverse events of acitretin is the muco-cutaneous adverse events. Dry lips being the most common one and be treated with the use of emollients. Others include dry dry mouth, cheilitis, stomatitis and gingivitis and taste disturbances. Acitretin causes dryness with inflammation of mucous membrane and transitional epithelia which occasionally leads to epistaxis, rhinitis, photophobia, conjunctivitis and xeropthalmia. Alopecia, nail-fragility and paronychia have also been observed(27). Rarely patients may have the photosensitivity reactions. Retinoid dermatitis which resembles unstable psoriasis can develop 25% of the patients receiving high dose of acitretin therapy(28). Muco cutaneous side effects can be treated symptomatically, and if severe effects occur the dose reduction can be tried before the discontinuation of the drug. Acitretin causes transient elevation of liver enzymes. The elevation is dose dependent and usually reverse back to normal after reducing the dose or after discontinuation of the therapy. Severe hepatotoxic reactions resulting from retinoids are rare. In a data of 1877 patients receiving oral acitretin only 0.26% of the patients showed overt chemical hepatitis(29). However, the hepato-toxic reactions in children are rare because the cofactors like diabetes, alcoholism, and obesity are less likely in children(12). Acitretin also exerts the effects on lipid profile which is reverse back to normal within 8 weeks after the discontinuation of the drug(30). Retinoids are seen to cause the elevation of triglyceride and cholesterol and decrease in the high density lipoprotein. In a study it is seen that 35% of the patients had the elevation in serum triglyceride above 300mg/dl and about 15% of the patients had the elevation of cholesterol level(31). The decrease in the high density lipoprotein is also observed(29). Retinoids have been known to cause the skeletal abnormalities especially in children. The long term treatment with etretinate is also associated with the extraspinal tendon and the calcification of ligament. However, the study including 19 children and young adults, treated with etretinate for continuous 5 years do not show any skeletal abnormality(32). No cases of diffuse idiopathic skeletal hyperostosis was seen in a retrospective study on long term use of acitretin in a low dose(33). No significant radiologic abnormalities associated with retinoids was detected in a patient of severe pustular psoriasis treated with low dose of acitretin for 9 years(34). It is usually not recommended to use oral retinoids for the treatment of psoriasis in children due to the report of occasional bone changes like premature epiphyseal closure, skeletal hyperostosis and extra-osseous calcification observed in the children on the long term treatment with etretinate(35, 36). If acitretin is to be used in a child, the child should be observed carefully for any abnormalities of growth and bone development. Routine radiography is not recommended because of the radiation hazards, but the atypical musculoskeletal pain must be investigated with x-rays. Growth chart of the child on acitretin should be maintained (27). Arthralgia, arthritis, myalgia may also occur during the treatment with acitretin. A few case of vasculitis, Wegener granulomatosis and erythema nodosum are also observed. Retinoids are teratogenic drugs. The defect due to retinoids is termed as retinoic acid embryopathy. The malformations seen in the fetus include microtia/anotia, micrognathia, cleft-palate, conotruncal heart disease and aortic arch abnormalities, thymic defects, retinal or optic nerve abnormalities and central nervous system malformations(37). Even though only one report of human teratogenicity due to acitretin has been published(27), acitretin should be cautiously used as acitretin is converted to etretinate which has a longer elimination half-life. The female patient of child-bearing should strictly be instructed for the use of two effective contraceptive method stating 1-month prior of treatment, during the period of treatment and 3 years after the discontinuation of treatment(38). However, the risk of teratogenicity by use of acitretin in children is less because of the least chance of a child to get pregnant. The concomitant use of retinoid with tetracycline and minocycline has led to pseudo-tumour cerebri(29). Pseudo-tumor cerebri was reported in a case of 14-year-old boy treated with isotretinoin and tetracycline(39). Retinoids also causes blurring of vision, headache and reduced night vision. Patient with severe headache, vomiting and visual disturbances should stop acitretin immediately and consult the doctor(27). The concomitant use of vitamin A with acitretin must be restricted. MONITORING GUDELINES: Before starting the treatment with acitretin, proper history taking and careful physical examination should be performed. Laboratory investigations including complete blood count, lipid profile, liver enzymes and blood sugar in diabetics should be done. Monitoring of the liver enzymes and fasting serum cholesterol and triglyceride must be done every 2-4 weeks of therapy for the first two months and then every three months(27). Children on acitretin therapy must have their growth charted. Female of child bearing age and their parents should be counselled about the teratogenic effect of the drug and use of contraception during and after the treatment. The pregnancy should be ruled out before the initiation of acitretin therapy with two negative pregnancy tests. CONCLUSION: Acitretin is a non-immunosuppressive drug that can be effective in the treatment of childhood psoriasis. It is seen that acitretin is more effective in pustular and erythrodermic psoriasis and moderately effective in the plaque type psoriasis in children. Acitretin is used both as monotherapy and as combination therapy. As the use of acitretin in children lack sufficient data and evidence, its use in children should always be weighed with risk benefit of treatment and risk if the disease is left untreated. The side effects are mostly dose dependent so it can be minimized by using the lowest possible dose. The dose of 0.5-1mg/kg/day was seen to be effective. It should be used cautiously in the female patient. Long term treatment with acitretin require proper clinical and laboratory evaluation. REFERENCES 1.Griffiths CE, Barker JN. Pathogenesis and clinical features of psoriasis. Lancet (London, England). 2007;370(9583):263-71. 2.Al-Mutairi N. Childhood Psoriasis: Springer International Publishing; 2016. 3.Raychaudhuri SP, Gross J. A comparative study of pediatric onset psoriasis with adult onset psoriasis. Pediatric Dermatology. 2000;17(3):174. 4.Kumar B, Jain R, Sandhu K, Kaur I, Handa S. Epidemiology of childhood psoriasis: a study of 419 patients from northern India. Digest of the World Core Medical Journals. 2004;43(9):654-8. 5.Seyhan M, CoÃ…Å ¸kun BK, SaÄÅ ¸lam H, Ozcan H, KarincaoÄÅ ¸lu Y. Psoriasis in childhood and adolescence: evaluation of demographic and clinical features. Pediatrics International Official Journal of the Japan Pediatric Society. 2006;48(6):525-30. 6.Fan X, Xiao FL, Yang S, Liu JB, Yan KL, Liang YH, et al. Childhood psoriasis: a study of 277 patients from China. Journal of the European Academy of Dermatology Venereology. 2007;21(6):762. 7.de Moll EH, Chang MW, Strober B. Psoriasis in adults and children: Kids are not just little people. Clinics in Dermatology. 2016;34(6):717. 8.Kimball AB, Wu EQ, Guerin A, Yu AP, Tsaneva M, Gupta SR, et al. Risks of developing psychiatric disorders in pediatric patients with psoriasis. Journal of the American Academy of Dermatology. 2012;67(4):651-7.e1-2. 9.Fox FE, Rumsey N, Morris M. Ur skin is the thing that everyone sees and you cant change it!: exploring the appearance-related concerns of young people with psoriasis. Developmental neurorehabilitation. 2007;10(2):133-41. 10.Burden AD. Management of psoriasis in childhood. Clinical and experimental dermatology. 1999;24(5):341-5. 11.Orfanos CE, Stadler R, Gollnick H, Tsambaos D. Current developments of oral retinoid therapy with three generations of drugs. Non-aromatic, monoaromatic and polyaromatic retinoids (arotinoids). Current problems in dermatology. 1985;13:33-49. 12.Gautam M, Tahiliani H, Nadkarni N, Patil S, Godse K. Acitretin in pediatric dermatoses. 2016;17(2):87. 13.Brecher AR, Orlow SJ. Oral retinoid therapy for dermatologic conditions in children and adolescents Journal of the American Academy of Dermatology. Journal of the American Academy of Dermatology. 2003;49(2):171-82. 14.Wiegand UW, Chou RC. Pharmacokinetics of acitretin and etretinate. Journal of the American Academy of Dermatology. 1998;39(2 Pt 3):S25-33. 15.McNamara PJ, Jewell RC, Jensen BK, Brindley CJ. Food increases the bioavailability of acitretin. Journal of clinical pharmacology. 1988;28(11):1051-5. 16.Grà ¸nhà ¸j Larsen F, Steinkjer B, Jakobsen P, Hjorter A, Brockhoff PB, Nielsenà ¢Ã¢â€š ¬Ã‚ Kudsk F. Acitretin is converted to etretinate only during concomitant alcohol intake. British Journal of Dermatology. 2000;143(6):1164-9. 17.Lacour M, Mehta-Nikhar B, Atherton DJ, Harper JI. An appraisal of acitretin therapy in children with inherited disorders of keratinization. The British journal of dermatology. 1996;134(6):1023-9. 18.Cordoro KM. Systemic and light therapies for the management of childhood psoriasis: part II. Skin Therapy Letter. 2008;13(4):1-3. 19.Ergun T, Seckin Gencosmanoglu D, Alpsoy E, Bulbul-Baskan E, Saricam MH, Salman A, et al. Efficacy, safety and drug survival of conventional agents in pediatric psoriasis: A multicenter, cohort study. J Dermatol. 2016. 20.Di LV, Bonamonte D, Lasagni C, Belloni FA, Cambiaghi S, Corazza M, et al. Effectiveness and Safety of Acitretin in Children with Plaque Psoriasis: A Multicenter Retrospective Analysis. Pediatric Dermatology. 2016;33(5):530-5. 21.Ergin S, Ersoy-Evans S, Sahin S, Ozkaya O. Acitretin is a safe treatment option for infantile pustular psoriasis. Journal of Dermatological Treatment. 2009;19(6):341-3. 22.Salleras M, Sanchez-Regaà ±a M, Umbert P. Congenital Erythrodermic Psoriasis: Case Report and Literature Review. Pediatric Dermatology. 1995;12(3):231-4. 23.Haug V, Benoit S, Wohlleben M, Hamm H. Annular pustular psoriasis in a 14-month-old girl: a therapeutic challenge. The Journal of dermatological treatment. 2017:1-6. 24.Marqueling AL, Cordoro KM. Systemic treatments for severe pediatric psoriasis: a practical approach. Dermatologic clinics. 2013;31(2):267-88. 25.de Oliveira ST, Maragno L, Arnone M, Fonseca Takahashi MD, Romiti R. Generalized pustular psoriasis in childhood. Pediatr Dermatol. 2010;27(4):349-54. 26.Kopp T, Karlhofer F, Szà ©pfalusi Z, Schneeberger A, Stingl G, Tanew A. Successful use of acitretin in conjunction with narrowband ultraviolet B phototherapy in a child with severe pustular psoriasis, von Zumbusch type. Digest of the World Core Medical Journals. 2005;151(4):912-6. 27.Ormerod AD, Campalani E, Goodfield MJ. British Association of Dermatologists guidelines on the efficacy and use of acitretin in dermatology. British Journal of Dermatology. 2010;162(5):952-63. 28.Kragballe K, Jansen CT, Geiger JM, Bjerke JR, Falk ES, Gip L, et al. A double-blind comparison of acitretin and etretinate in the treatment of severe psoriasis. Results of a Nordic multicentre study. Acta dermato-venereologica. 1989;69(1):35-40. 29.Katz HI, Waalen J, Leach EE. Acitretin in psoriasis: an overview of adverse effects. Journal of the American Academy of Dermatology. 1999;41(3 Pt 2):S7-s12. 30.Vahlquist C, Selinus I, Vessby B. Serum lipid changes during acitretin (etretin) treatment of psoriasis and palmo-plantar pustulosis. Acta dermato-venereologica. 1988;68(4):300-5. 31.Gupta AK, Goldfarb MT, Ellis CN, Voorhees JJ. Side-effect profile of acitretin therapy in psoriasis. Journal of the American Academy of Dermatology. 1989;20(6):1088-93. 32.Glover MT, Peters AM, Atherton DJ. Surveillance for skeletal toxicity of children treated with etretinate. The British journal of dermatology. 1987;116(5):609-14. 33.Lee E, Koo J. Single-center retrospective study of long-term use of low-dose acitretin (Soriatane) for psoriasis. The Journal of dermatological treatment. 2004;15(1):8-13. 34.Halverstam CP, Zeichner J, Lebwohl M. Lack of significant skeletal changes after long-term, low-dose retinoid therapy: case report and review of the literature. Journal of cutaneous medicine and surgery. 2006;10(6):291-9. 35.Prendiville J, Bingham EA, Burrows D. Premature epiphyseal closurea complication of etretinate therapy in children. Journal of the American Academy of Dermatology. 1986;15(6):1259-62. 36.Halkier-Sorensen L, Laurberg G, Andresen J. Bone changes in children on long-term treatment with etretinate. Journal of the American Academy of Dermatology. 1987;16(5 Pt 1):999-1006. 37.Lammer EJ, Chen DT, Hoar RM, Agnish ND, Benke PJ, Braun JT, et al. Retinoic acid embryopathy. The New England journal of medicine. 1985;313(14):837-41. 38.Sarkar R, Chugh S, Garg VK. Acitretin in dermatology. Indian journal of dermatology, venereology and leprology. 2013;79(6):759-71. 39.Lee AG. Pseudotumor cerebri after treatment with tetracycline and isotretinoin for acne. Cutis. 1995;55(3):165-8.

Wednesday, November 13, 2019

Clarissa or The History of a Young Lady :: Clarissa History of a Young Lady

Clarissa or The History of a Young Lady    In the Johnson age there are many popular writers.   One of these authors is Samuel Richardson, who was a novelist.   His most popular novels were Pamela and Clarissa, which are both constructed of a series of letters.   Clarissa, however, was regarded as one of his most popular European novels.   "His masterpiece, Clarissa, or the History of a Young Lady, one of the greatest European novels, was published in 1747-8" (Richardson, 1).    When Richardson wrote Clarissa his intention was to write a novel of a series of letters that were written by an unskilled author.   This book contains 537 letters written by various characters in the novel.   Because the book is so long I could not read the whole thing nor have   I ever read it before.   As a result I can not say a lot about it.   Because I find it is a little hard to read I was not able to read as much as I would have like to in the four hours that we were to set aside to read the book.   I did, however, manage to read the first eight letters in the novel.   The first letter was written to Clarissa Harlowe from her good friend Anna Howe.   This letter is used to introduce the reader to the problems that have been going on in the Harlowe home that lead to Clarissa being the topic of gossip.    The letters that follow this one are from Clarissa to Anna and they explain what had happened.   The trouble begins when Mr. Lovelace begins to visit the Harlowe home; it is believed that he is there to court the eldest daughter.   However, this does not work out and he then decides the he would like to date the younger daughter, who is Clarissa.   This is not well liked by her brother because Mr. Lovelace was his enemy all through college and there is now a grudge between the two.   As a result, Clarissa's brother and Mr. Lovelace get into a fight and Clarissa's brother is injured.   It is because of this that no one else in the family cares for him anymore either.   However, this does not stop him from pursuing Clarissa.